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The Opioid Treatments for Chronic Pain report compares prescribed systemic opioids with placebo, other opioids, and non-opioid drugs or noninvasive nonpharmacologic therapy for any chronic pain conditions. AHRQ shared that the purpose of this review is to "assess the effectiveness and harms of opioid therapy for chronic noncancer pain, alternative opioid dosing strategies, and risk mitigation strategies."

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